Vision For Life

Corneal Cross-linking

What is corneal cross-linking?

Corneal cross-linking is a treatment performed on the cornea to stop keratoconus worsening.  If left untreated, keratoconus can result in permanent loss of vision that can only be treated with a corneal transplant.

Cross-linking surgery has revolutionised the treatment of keratoconus as blindness can be prevented if performed.  

During the procedure, riboflavin (vitamin B2) drops are applied to the cornea and the cornea is exposed to ultraviolet light (UVA). This causes a chemical reaction which results in chemical bonds (cross links) to form between the collagen fibers in the cornea.

Corneal cross-linking surgery results in the cornea becoming stiffer. As a result, the keratoconus is much less likely to progress.

There is very good evidence from large studies around the world that this is an effective treatment in stopping keratoconus progression.

Without cross-linking, at least 20% of all patients with keratoconus will eventually require a corneal transplant. One of the goals of cross-linking is to avoid the need for a corneal transplant.

Does cross-linking improve my vision?

No.  The goal of cross-linking is to stop keratoconus worsening, not to improve vision.

What happens during corneal cross-linking?

Cross linking is performed with local anaesthetic drops so there is minimal discomfort felt during the procedure.

You will be awake during the procedure.

The procedure is performed with you lying down.

In the first step, the surface layer of the cornea is removed. This is an unusual sensation but is not painful.

After this riboflavin eye drops are placed on the cornea every few minutes for 30 minutes.

Following this, a small clip is inserted to keep the eyelids open and the UV light is applied to the cornea for 10 minutes.

Following this a soft contact lens is placed on the cornea. This helps to reduce pain and speeds up healing.