Corneal cross-linking

Corneal cross-linking is a treatment performed on the cornea to stop keratoconus worsening.  If left untreated, keratoconus can result in permanent loss of vision that can only be treated with a corneal transplant. Cross-linking surgery has revolutionised the treatment of keratoconus as blindness can be prevented if performed. During the procedure, riboflavin (vitamin B2) drops are applied to the cornea and the cornea is exposed to ultraviolet light (UVA). This causes a chemical reaction which results in chemical bonds (cross links) to form between the collagen fibers in the cornea. Corneal cross-linking surgery results in the cornea becoming stiffer. As a result, the keratoconus is much less likely to progress. There is very good evidence from large studies around the world that this is an effective treatment in stopping keratoconus progression. Without cross-linking, at least 20% of all patients with keratoconus will eventually require a corneal transplant. One of the goals of cross-linking is to avoid the need for a corneal transplant.